Accession Number:

AD0676147

Title:

GLUCOSE TOLERANCE IN DOGS EXPOSED TO ALTITUDE AND DRUG ADMINISTRATION: MEPERIDINE.

Descriptive Note:

Rept. for Oct-Dec 67,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1968-06-01

Pagination or Media Count:

12.0

Abstract:

The rate of disappearance of an injected glucose load from the blood of dogs exposed to a simulated altitude of 27,000 ft. was compared to similar glucose tolerance at ground level. All dogs were anesthetized and maintained on the same PO2 in the inspired air 152 mm. Hg PO2. In addition, 2.0 mg.kg. Demerol meperidine were administered intravenously to the dogs under both atmospheric conditions. A significant increase was seen in the K-value of the nondrug dogs exposed to simulated altitude P .05. There was no significant difference between drug and nondrug dogs at altitude or between drug and nondrug dogs at ground level. Author

Subject Categories:

  • Stress Physiology
  • Toxicology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE