PHARMACOLOGICAL IMPROVEMENT OF CAPACITY OF PULMONARY CIRCULATION AT HIGH ALTITUDE.
Rept. no. 2 (Final) Apr 67-Apr 68,
TOHO UNIV TOKYO (JAPAN) DEPT OF PHYSIOLOGY
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The effect of ascorbic acid on increasing tolerance to hypoxia has been proved. The noticeable findings have been found in our experiments 1 ascorbic acid moves from organs to blood in hypoxia and 2 the proportion of oxydized ascorbic acid is much larger in the heart than any other organs in hypoxia. The explanation for these findings have not yet been given. However, these results suggest that there may be some important relationship between ascorbic acid and heart activity which was proved in our previous experiments to be the most significant factor limiting the altitude tolerance. Author
- Anatomy and Physiology