Accession Number:

AD0673312

Title:

THE SPREAD FACTOR OF THE PLAGUE BACILLUS. COMMUNICATION II. DISCOVERY OF HYALURONIDASE IN THE PLAGUE BACILLUS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1968-07-01

Pagination or Media Count:

12.0

Abstract:

The experiments were performed for the purpose of determining whether active plague preparations which develop the spread phenomenon in vivo contain the enzyme hyaluronidase. The detection of hyaluronidase in vitro is based upon the fact that because of its action hyaluronic acid loses its ability to form a clot in an acid medium, its viscosity is decreased depolymerization and it is hydrolytically decomposed into glucuronic acid and glucosamine.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE