THE CLINICAL ASPECTS, DIAGNOSIS AND EPIDEMIOLOGY OF HISTOPLASMOSIS
ARMY BIOLOGICAL LABS FREDERICK MD
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Histoplasmosis in adults can have an acute, subacute, or chronic course. In children, particularly in the early ages, the disease has an acute character. All of the organs and tissues of the organism and above all the reticuloendothelial system can be afflicted in this disease. In connection with this its clinical manifestations are extremely varied. Generalized histoplasmosis is accompanied by an irregular type fever, splenohepatomegaly, anemia, lymphadenopathy, and sharp emaciation.
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