Accession Number:

AD0673020

Title:

THE CULTIVATION OF VIRUSES OF THE TICK-BORNE ENCEPHALITIS GROUP ON MONKEY-HEART CELLS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1968-07-01

Pagination or Media Count:

8.0

Abstract:

The viruses of tick-borne encephalitis, diphasic meningoencephalitis, and louping ill propagate actively in cultures of monkey-heart cells. All of the investigated strains of the viruses induce a marked cytopathogenic effect from the first cultural passage. The cytopathogenic effect is retained in further subinoculation. The specificity of the cytopathogenic effect of the viruses of the tick-borne encephalitis group is determined in the neutralization test with a homologous immune serum in a tissue culture. A comparative titration of the viruses in a tissue culture and in the tests of intracerebral inoculation of white mice gives practically identical results.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE