ANTHRAX TOXIN: PRIMARY SITE OF ACTION
FORT DETRICK FREDERICK MD
Pagination or Media Count:
Administration of anthrax toxin via the cerebrospinal fluid demonstrates positively that the toxin alters the bodys physiology, primarily via the central nervous system, and kills by terminal anoxia mediated by the central nervous system. The use of a positive-pressure respirator and isoproterenol prevented death in animals that had received lethal doses of toxin. This demonstration of therapy for a lethal bacterial toxin opens new avenues of investigation.
- Medicine and Medical Research