Accession Number:

AD0657797

Title:

WATER INSOLUBLE DERIVATIVES OF PROTEINS WITH BIOLOGICAL ACTIVITY.

Descriptive Note:

Final technical rept. 1 Jul 66-30 Jun 67,

Corporate Author:

WEIZMANN INST OF SCIENCE REHOVOTH (ISRAEL)

Personal Author(s):

Report Date:

1967-06-30

Pagination or Media Count:

20.0

Abstract:

A number of derivatives of papain and chymotypsin were prepared in which the active enzyme was covalently bound to a high-molecular weight carrier e.g., poly-L-ornithyl papain, poly-L-glutamyl chymotrypsin. A kinetic study was made of these compounds, with particular attention given to pH activity profiles. Papain-collodion membranes were also prepared and were examined with respect to the effect of local gradients of enzyme and substrate on their kinetic activity.

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE