Accession Number:

AD0657673

Title:

THE EVALUATION OF VASOACTIVE AGENTS IN SHOCK WITH AND IN THE ABSENCE OF INTRAVENOUS FLUID THERAPY

Descriptive Note:

Annual progress rept. 1 Dec 1966-1 Aug 1967

Corporate Author:

PENNSYLVANIA UNIV PHILADELPHIA HARRISON DEPT OF SURGICAL RESEARCH

Personal Author(s):

Report Date:

1967-08-01

Pagination or Media Count:

6.0

Abstract:

The report deals with the following areas of study related to vasoactive agents and fluid therapy in shock 1 The effects of beta- adrenergic receptor stimulation on blood flow, oxidative metabolism and survival in hemorrhagic shock dose--response relationships in differing circumstances, survival studies with continuous Isoproterenol infusion, oxygen consumption and excess lactate with Isoproterenol 2 Hepato-splanchnic lymph production with hydrocortisone treated endotoxin shock 3 The ventilatory response to hemorrhage alterations in the response of ventilation to carbon dioxide, studies in awake animals, carotid sinus denervation and vagal-sympathetic trunk division 4 Dynamic alterations in the volume of distribution of anions in hemorrhagic hypotension and hypoxemia 5 The hemodynamic and metabolic effects of lactated Ringers solution in hemorrhagic shock.

Subject Categories:

  • Medicine and Medical Research
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE