Accession Number:

AD0655345

Title:

A MATHEMATICAL MODEL FOR POST-IRRADIATION HEMATOPOIETIC RECOVERY,

Descriptive Note:

Corporate Author:

RAND CORP SANTA MONICA CALIF

Personal Author(s):

Report Date:

1967-07-01

Pagination or Media Count:

40.0

Abstract:

A mathematical model is presented of the recovery after irradiation of the system producing blood cells in the body. The model is based on the hypothesis that hematopoietic stem cells, which are unable to reproduce as stem cells following irradiation, may still retain an ability to differentiate. The model demonstrates both an abortive recovery rise and a true recovery rise following irradiation. As a first approximation, the model shows no irreconcilable differences from experimental data and generally represents the phenomena observed in the recovery of erythropoiesis following acute irradiation. In addition, certain postulates basic to blood-cell development are derived. Author

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE