TECHNIQUES USED IN THE ESTABLISHMENT OF A SUSTAINED-BARRIER MOUSE-BREEDING COLONY.
Technical rept. May-Dec 66,
EDGEWOOD ARSENAL MD
Pagination or Media Count:
The report describes the establishment of an infectious-disease-free colony of mice from germ-free stock. The mice subsequently became contaminated with a defined group of organisms. It was concluded that a sustained-barrier mouse colony, free from many microorganisms found in conventional colonies, can be developed from carefully screened, commercially supplied, germ-free mice. The chief source of contamination in colony rooms was the working staff, even though rigorous precautions were taken to insure cleanliness. Author
- Animal Husbandry and Veterinary Medicine