Accession Number:

AD0654292

Title:

RAPID TRANSFER OF CORTISOL FROM THE BLOODSTREAM TO PAROTID FLUID.

Descriptive Note:

Rept. for 1 Apr-31 May 66,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1967-04-01

Pagination or Media Count:

13.0

Abstract:

The time required for injected cortisol to appear in significant quantity in parotid fluid has been determined in healthy young adult males. Following intravenous injection, a significant P .01 increase in 17-OHCS concentration in parotid fluid was detectable in samples collected from the time of injection to 5 minutes thereafter. When cortisol was administered intramuscularly, the parotid 17-OHCS concentration increased significantly P .01 at 15 minutes after dosage. This rapid transfer of cortisol from the blood stream to parotid fluid suggests that parotid fluid steroid measurements possess potential in monitoring adrenocortical responses of even a fleeting nature. Author

Subject Categories:

  • Biochemistry
  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE