Accession Number:

AD0654290

Title:

EFFECT OF URICOSURIC DRUG ADMINISTRATION ON URIC ACID LEVELS IN UNSTIMULATED PAROTID FLUID.

Descriptive Note:

Rept. for 10-30 May 65,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Personal Author(s):

Report Date:

1967-04-01

Pagination or Media Count:

10.0

Abstract:

Parotid fluid was collected twice daily without exogenous stimulation from 6 healthy young adult males, both before and during a 5-day period of uricosuric drug dosage. A highly significant decrease in serum uric acid concentration was brought about by drug administration and a parallel decrease was found in parotid fluid uric acid concentration and uric acid secretion rate. The mean for serum uric acid decreased from 5.40 to 2.06 mg.100 ml. and parotid fluid uric acid concentration fell from 10.16 to 4.23 mg.100 ml. morning samples and 7.29 to 3.90 mg.100 ml. afternoon samples. Author

Subject Categories:

  • Anatomy and Physiology
  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE