EFFECT OF URICOSURIC DRUG ADMINISTRATION ON URIC ACID LEVELS IN UNSTIMULATED PAROTID FLUID.
Rept. for 10-30 May 65,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
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Parotid fluid was collected twice daily without exogenous stimulation from 6 healthy young adult males, both before and during a 5-day period of uricosuric drug dosage. A highly significant decrease in serum uric acid concentration was brought about by drug administration and a parallel decrease was found in parotid fluid uric acid concentration and uric acid secretion rate. The mean for serum uric acid decreased from 5.40 to 2.06 mg.100 ml. and parotid fluid uric acid concentration fell from 10.16 to 4.23 mg.100 ml. morning samples and 7.29 to 3.90 mg.100 ml. afternoon samples. Author
- Anatomy and Physiology
- Medicine and Medical Research