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COMPARATIVE STUDY OF ALLERGIC REACTIONS IN MONKEYS TO P.P.D. AND KOCH'S OLD TUBERCULIN.
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
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P.P.D. possesses obvious advantages over Kochs old tuberculin relative to sensitivity after BCG vaccination. Monkeys show a 50 positive reactivity to P.P.D. and only 16 to Kochs old tuberculin. In lower monkeys, Kochs old tuberculin elicits no allergic reaction, through P.P.D. does. Using this fact, Burnets hypothesis concerning allergy in lower monkeys was demonstrated to be untenable. Follow-up tuberculin reactivity tests conducted one year later indicated no essential deviation in further allergic reaction development in monkeys. Author
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