THE EFFECT OF RATE OF GLAND FUNCTION ON PAROTID FLUID URIC ACID LEVELS.
Rept. for 1 Sep-30 Nov 66,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
Pagination or Media Count:
Paired parotid fluid samples were collected without exogenous stimulation and at 5 different gustation-induced rates of flow. Enzymatic uric acid analyses were carried out to ascertain which of the collection procedures was least susceptible to the effect of flow rate on uric acid concentration. The comparative value of the unstimulated sample has not been delineated in the present study, but the extremely high concentration of uric acid in this type of fluid is suggestive of glandular alteration and raises questions concerning the validity of its use. For the stimulated samples the correlation coefficient for flow versus uric acid level, 5 -.852, was highly significant P .001. The effect of flow rate on uric acid concentration diminished as flow rate increased. It is suggested that parotid fluid samples for uric acid analysis should be collected at flow rates of 0.7 ml.min. or more. Author