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PRESERVATION OF RED CELLS IN THE FROZEN STATE WITH SUGARS AND MACROMOLECULAR ADDITIVES: MECHANISM OF INJURY OF FREEZING.
Progress rept. no. 62,
JOHN S SHARPE RESEARCH FOUNDATION BRYN MAWR PA
Pagination or Media Count:
The storage of ACD blood can be extended to eight weeks if the blood is incubated with adenine-inosine at the end of the storage period, when measure of viability is based on the accepted standard of an average survival of 70 or better of radioactivity of Cr51 tagged erythrocytes 24 hours posttransfusion. Evidence is presented suggesting that the absolute increase in ATP following incubation with adenine-inosine may not per se be solely responsible for the increased viability of erthrocytes. Author
APPROVED FOR PUBLIC RELEASE