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WHOLE ORGAN FREEZING AND THAWING HEAT TRANSFER AND THERMAL PROPERTIES.
Annual rept., 1 Apr 66-31 Mar 67,
GEOSCIENCE LTD LA JOLLA CALIF
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An alternate thermal conductivity device cylindrical geometry has been constructed and used to compliment the flat plate apparatus. Some thermal conductivity measurements for ice over the temperature range of 20F to -320F have been obtained and compared to literature values. Some difficulties have been encountered with entrapped air. Conductivity measurements for bovine liver in the unfrozen and frozen states were also made and compared to the behavior of water and ice. On the basis of the composition of liver, the results for liver were in reasonable agreement with the data for ice and water. A thermal gradient calorimeter has been designed, fabricated, calibrated and used to study the heat capacities of biological specimens. Heat capacity measurements have been made for ice, water, frozen bovine liver, kidney, skin, spleen, heart and calf liver. These heat capacity measurements were compared to the values known for water and ice. A graphical or numerical heat transfer procedure has been used to perform freezing calculations that are applicable to transient freeze-thaw heat transfer in organ and tissue storage. Specifically, the time-temperature histories in idealized slab organs with different amounts of water content have been calculated. Also, an analytical heating solution has been derived that defines the initial portion of the thawing history in a biological material that has embedded iron particles that are heated by electromagnetic induction. Author
APPROVED FOR PUBLIC RELEASE