THE EFFECTS OF AMBIENT PRESSURE ON TOLERANCE OF MAMMALS TO AIR BLAST
Technical progress rept.
LOVELACE FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH ALBUQUERQUE NM
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Seventy-six dogs, 43 goats, 211 rats and 255 guinea pigs were exposed to reflected shock pressures at ambient pressures ranging from 5 to 42 psia in air-driven shock tubes. Animal tolerance, expressed as LD50-one-hour overpressures rose progressively as the ambient pressure was increased. By analysis of the results of this study, combined with those from previous shock- tube investigations, a general equation for the regression of LD50 pressure on ambient pressure for mammals was derived. From this equation and previous estimates of the LD50 pressure for mans tolerance to overpressures of 400-msec duration at an ambient pressure of 12 psia, an equation relating LD50 pressure to ambient pressure was developed for the 70-kg mammal.
- Weapons Effects (Biological)