Accession Number:

AD0652672

Title:

ELECTRON MICROSCOPE STUDIES INTO THE MORPHOLOGY AND LOCALIZATION OF OMSK HEMORRHAGIC FEVER VIRUS IN INFECTED TISSUE CULTURE CELLS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Report Date:

1966-08-01

Pagination or Media Count:

13.0

Abstract:

During an investigation of a transplanted tissue culture of a swine embryo kidney, infected with the OHF virus, cytoplasmic oxyphilic inclusions were detected in the infected cells and their submicroscopic structure was revealed. Hypertrophy and hyperplasia of the endoplasmic network and the Golgi complex are noted during the process of virus multiplication. The Omsk hemorrhagic fever virus has a spherical or polygonal form. Its diameter equals 37 plus or minus 2 m millimicrons. In the center of the virus particle is a dense nucleoid with a diameter of about 25 millimicrons the peripheral zone is formed by a membrane consisting of 2 layers, apparently corresponding to the capsid and the lipid cover.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE