ABNORMAL PHOSPHORUS METABOLISM IN A POTASSIUM TRANSPORT MUTANT OF ESCHERICHIA COLI.
Report for Jan-Nov 66,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
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Studies with K transport mutant, strain RD-2, reveal that the mutant does not take up inorganic phosphorus normally. The abnormality in phosphorus uptake is reflected in a reduced rate of 32P sub i incorporation into phospholipid. The 32P sub i uptake reaction of the mutant is superstimulated by potassium and inhibited by sodium, characteristics which resemble the behavior of the potassium-stimulated enzymes that are most commonly found catalyzing reactions in intermediate metabolism that involve the transfer of a phosphate group. Author