LIVER BIOPSY IN HUMAN LEPTOSPIROSIS.
SAO PAULO UNIV (BRAZIL) INSTITUTO DE MEDICINA TROPICAL
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Liver biopsies of proved human cases of leptospirosis showed partial disappearance andor distortion of bile ductules and sinusoidal pole microvilli. The more severe cases showed definite mitochondrial pathology. Enlargement of the intercellular spaces was rarely seen. In leptospirosis there is a non specific cellular injury which could be the result of a toxin. Complete cell necrosis was not prominent, this finding being in accordance with the low level of serum transaminase seen in the disease. Author
- Medicine and Medical Research