Accession Number:

AD0650132

Title:

MATHEMATICAL ANALYSIS AND DIGITAL SIMULATION OF THE RESPIRATORY CONTROL SYSTEM

Descriptive Note:

Corporate Author:

RAND CORP SANTA MONICA CA

Report Date:

1967-03-01

Pagination or Media Count:

53.0

Abstract:

The report expresses the basic material balance relationships for the lung-blood-tissue gas transport and exchange system in a set of differential- difference equations containing a number of dependent time delays. Additional equations define the chemical details of transport and acid-base buffering, concentration equilibria, and blood flow behavior. Finally, a control function is included defining the dependence of ventilation upon CSF H, and arterial H and PO2 at the carotid chemoceptors. A Fortran program was written for convenient digital simulation of the responses of the system to a wide variety of forcings, including CO2 inhalation, hypoxia at sea level, altitude hypoxia, and metabolic disturbances in acid-base balance. Both dynamic and steady-state behavior of the model were reasonably realistic.

Subject Categories:

  • Bionics

Distribution Statement:

APPROVED FOR PUBLIC RELEASE