Accession Number:
AD0650132
Title:
MATHEMATICAL ANALYSIS AND DIGITAL SIMULATION OF THE RESPIRATORY CONTROL SYSTEM
Descriptive Note:
Corporate Author:
RAND CORP SANTA MONICA CA
Personal Author(s):
Report Date:
1967-03-01
Pagination or Media Count:
53.0
Abstract:
The report expresses the basic material balance relationships for the lung-blood-tissue gas transport and exchange system in a set of differential- difference equations containing a number of dependent time delays. Additional equations define the chemical details of transport and acid-base buffering, concentration equilibria, and blood flow behavior. Finally, a control function is included defining the dependence of ventilation upon CSF H, and arterial H and PO2 at the carotid chemoceptors. A Fortran program was written for convenient digital simulation of the responses of the system to a wide variety of forcings, including CO2 inhalation, hypoxia at sea level, altitude hypoxia, and metabolic disturbances in acid-base balance. Both dynamic and steady-state behavior of the model were reasonably realistic.
Descriptors:
- *RESPIRATORY SYSTEM
- *BIONICS
- COMPUTER PROGRAMS
- MATHEMATICAL MODELS
- TISSUES(BIOLOGY)
- CONTROL SYSTEMS
- ACID BASE EQUILIBRIUM
- DYNAMICS
- HYPOXIA
- CARBON DIOXIDE
- METABOLIC DISEASES
- CHEMORECEPTORS
- BLOOD CIRCULATION
- BLOOD
- DIGITAL COMPUTERS
- RESPONSE(BIOLOGY)
- COMPUTER LOGIC
- DIFFERENCE EQUATIONS
- GASES
- TRANSPORT PROPERTIES
- DIFFERENTIAL EQUATIONS
- LUNG
Subject Categories:
- Bionics