Accession Number:

AD0648224

Title:

INFLUENCE OF INTERMITTENT 98 PERCENT OXYGEN AND 380 MM. HG TOTAL PRESSURE ON SUSCEPTIBILITY TO TULAREMIA.

Descriptive Note:

Final rept., May-Jun 66,

Corporate Author:

SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX

Report Date:

1967-01-01

Pagination or Media Count:

10.0

Abstract:

Mice were conditioned by exposure three times per week for 2 weeks to an atmosphere of 97 to 99 oxygen at 380 mm. Hg total pressure for 2 or 8 hours per exposure. They were then infected intraperitoneally with Pasteurella tularensis and either exposed daily to the same test conditions or kept at ground level under normal conditions. The results indicate that the length of the exposure period 2 or 8 hours did not influence host susceptibility however, increased susceptibility was observed in animals exposed to the test conditions before infection regardless of whether or not they were further exposed subsequent to challenge. Conditioned animals receiving additional exposure were not more susceptible than those retained under normal conditions after infection. Author

Subject Categories:

  • Stress Physiology
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE