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ENERGY METABOLISM OF RATS BORN AND RAISED IN LOW-PRESSURE PURE OXYGEN ENVIRONMENT.
Rept. for Nov 64-Oct 66,
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TEX
Pagination or Media Count:
Ten rats born and maintained in a pure oxygen environment at a total pressure of 210 mm. Hg absolute were placed individually in metabolism cages at 21 days of age and remained there for 6 weeks. They were compared with a similar group of ground-level controls. In additon, 6 rats maintained at altitude and 6 controls were sacrificed at 21 days of age to provide an initial estimate of whole-body energy. Growth rates did not differ significantly however, overall digestibility was lowered in experimentals, 74.3 versus 79.5 for controls P .001, with even greater differences in protein digestibility, 65.5 versus 74.6 P .001. Although less fat was also digested by experimentals, 75.6 versus 81.4, this difference was not significant. Net caloric intake for both groups was the same, however, as a result of increased food intake by experimentals. Calories given off as heat did not differ, suggesting similar metabolic rates. Carcass content of fat and protein, as a percentage of dry matter, did not differ for 21- or 63- day-old rats. The 21-day-old experimentals had a higher water content, 68.1 versus 65.6 for controls P .05. Caloriesgram on a dry-weight basis showed no significant differences in either the 21- or 63-day group. Author
APPROVED FOR PUBLIC RELEASE