Accession Number:

AD0648115

Title:

CAUSES UNDERLYING THE LOWERING OF THE NATURAL RESISTANCE OF IRRADIATED ANIMALS TO LIVE BRUCELLOSIS VACCINE

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1966-05-01

Pagination or Media Count:

9.0

Abstract:

An increase in the death of irradiated laboratory animals was observed following the administration of live or heat killed vaccine cultures of brucella, and also by the administration of the endotoxin which was extracted from them. The intensity of seeding of organs by the brucella vaccine strain was not intensified and its residual virulence was not increased. In the lowering of the resistance of irradiated animals to the vaccine strain, Br. abortus No 19-BA, a leading role resides in the increased sensitivity to the brucella endotoxin.

Subject Categories:

  • Medicine and Medical Research
  • Radiobiology
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE