Accession Number:

AD0648108

Title:

A MODIFICATION OF CHICK EMBRYO RESISTANCE TO VARIOUS INFECTIONS UNDER THE EFFECT OF POLYSACCHARIDES ISOLATED FROM NONPATHOGENIC MICROBES

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1966-05-01

Pagination or Media Count:

10.0

Abstract:

Biologically active polysaccharides from nonpathogenic microorganisms -- acetoxan, prodigiosin and glucose -- are capable of stimulating the nonspecific resistance of embryos to certain infections. In the early stages of development the chick embryos did not react to the administration of biologically active polysaccharides with a sufficient increase of resistance to a number of bacterial infections. As a measure of the development of the embryos, this capability was intensified and was well expressed and comparatively stable in 13-day embryos, and in 15-day embryos it reached a still higher level. At this age the administration of polysaccharides changed the development of infection in the embryos not only when they were administered prophylactically, but also when administered simultaneously with infection or following infection. Additional investigations are required for clearing up this peculiarity.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE