Accession Number:

AD0648100

Title:

EFFECT OF PLAGUE TOXIN ON RESPIRATORY ENZYMES,

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL CENTER FREDERICK MD

Personal Author(s):

• Krupenina,V. N.

Report Date:

1964-12-01

Pagination or Media Count:

9.0

Abstract:

Intraperitoneal injection of white rats with plague toxin reduces succinic dehydrogenase and cytochrome oxidase activity and activates catalase. Plague toxin has no effect on the activity of succinic dehydrogenase, cytochrome oxidase, and catalase in in vitro experiments. The action of toxic fractions of the plague bacillus on the respiration of white rats is based not on the direct but on the indirect effect of the toxin on the activity of the oxidation enzymes of the mitochondria. Author

Descriptors:

• *YERSINIA PESTIS
• *TOXINS AND ANTITOXINS
• *ENZYMES
• DISEASES
• IN VITRO ANALYSIS
• TOXICITY
• INJECTIONS(MEDICINE)
• OXIDOREDUCTASES
• RESPIRATION
• MITOCHONDRIA
• RATS
• USSR

Subject Categories:

• Medicine and Medical Research
• Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE