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Accession Number:
AD0647723
Title:
CHANGES IN THE MORPHOLOGICAL COMPOSITION OF BLOOD IN EXPERIMENTAL PLAGUE
Descriptive Note:
Corporate Author:
FORT DETRICK FREDERICK MD
Report Date:
1965-06-01
Pagination or Media Count:
13.0
Abstract:
A method is proposed for taking blood with a graduated pipette and diluting it in test tubes. The method is safe for working with plague infected animals. Following the infection of guinea pigs and white mice with a virulent strain of plague microbe the number of erythrocytes in 1 cu mm of blood increased on all the days following infection. In the first days of plague infection leukocytosis was observed in the animals, sometimes hyperleukocytosis, which on the 4--5th day following infection was replaced by leukopenia. The number of blood platelets increased in the first 3 days after infection and decreased in cases of a prolonged course of infection.
Distribution Statement:
APPROVED FOR PUBLIC RELEASE