Accession Number:

AD0647617

Title:

A STUDY OF CALCIUM, PHOSPHORUS, AND NITROGEN MOBILIZATION RESULTING FROM CONDITIONS OF INACTIVITY IN MACACA IRUS MONKEYS.

Descriptive Note:

Final rept.,

Corporate Author:

SOUTHWEST RESEARCH INST SAN ANTONIO TEX

Personal Author(s):

• Gross,Arthur L.
• Roberson,Kenneth T.
• Krough,Louis H. , Jr.
• Miesse,John W.

Report Date:

1966-11-01

Pagination or Media Count:

47.0

Abstract:

A study was made of calcium, nitrogen, and phosphorus balance resulting during conditions of inactivity. Monkeys, Macaca irus, were inactivated by three different methods surgical denervation, plaster casts, and tranquilization. The monkeys were placed in the plaster casts either in the sitting position or in the supine position. Balance studies were conducted by measuring food intake and urine and fecal output of calcium, nitrogen, and phosphorus. Calcium was measured by flame photometry, and nitrogen and phosphorus were measured colorimetrically. The animals inactivated by surgical denervation and plaster casts experienced what appeared to be a negative nitrogen balance which could be attributed to disuse atrophy of skeletal muscles. The urinary phosphorus excretion increased in the inactivated animals by severalfold but there was no overall reduction in the total phosphorus excreted. No noticeable changes in calcium balance were observed in the inactivated animals. Author

Descriptors:

• (*BONES
• DEGRADATION)
• (*CALCIUM
• METABOLISM)
• (*PHOSPHORUS
• METABOLISM)
• (*RELAXATION(PHYSIOLOGY)
• STRESS(PHYSIOLOGY))
• AEROSPACE MEDICINE
• MONKEYS
• VETERINARY MEDICINE
• PHYSIOLOGY

Subject Categories:

• Anatomy and Physiology
• Stress Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE