Accession Number:

AD0647148

Title:

DIFFERENTIATION BETWEEN PROTEOLYTIC AND TAME ESTEROLYTIC ACTIVITY IN CROTALUS ATROX VENOM.

Descriptive Note:

Interim rept.,

Corporate Author:

ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s):

Report Date:

1966-12-12

Pagination or Media Count:

18.0

Abstract:

Although Crotalus atrox venom can hydrolyze proteins and arginine esters, these activities are not due to a trypsin-like enzyme. Proteolytic and esterolytic activities have been differentiated by specific inhibition by such compounds as PMSF, DFP, EDTA and 2-mercaptoethanol, and by actual resolution of the venom by DEAE-cellulose chromatography. Preliminary results suggest that the proteolytic activity in the venom may have a limited specificity and that this specificity is quite unlike that of trypsin and plasmin. Author

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE