Accession Number:

AD0645566

Title:

FASCIA DEFECTS HOMOPLASTIC REPAIR WITH FROZEN AND LYOPHILIZED FASCIA,

Descriptive Note:

Corporate Author:

NAVAL MEDICAL SCHOOL BETHESDA MD TRANSLATION SERVICE

Personal Author(s):

Report Date:

1966-10-20

Pagination or Media Count:

10.0

Abstract:

The preserved fascia in homografts, just like the fresh fascia in autografts, after being transplanted into fascia defects makes connection with the hosts bed by means of granulation tissue, which later matures into dense connective tissue. In the first few days following transplanting, the nuclei of the connective tissue do not stain homogenization of the collagen structure occurs. The majority of cells are preserved in the autografts. At 7 to 16 days diffuse proliferation of granulation tissue cells into the homografts is seen, with subsequent formation of collagen fibers in the presence of dystrophic changes in the fibers of the graft proper. In the homografts, after 6 months, the newly formed connective tissue, replacing the transplanted fascia, acquires a structure similar to the usual fascia structure. No essential difference is observed between the homograft fascia and the autograft of fresh fascia. The main difference between the homografts and autograft fascia is that in autografts the elements of the graft proper are preserved to a marked degree. Homografts of lyophilized and frozen fascia in the experiments underwent identical changes their cells underwent necrosis cells of granulation tissue of the host proliferated into the collagen matrix. After that, the grafts became substituted for by new connective tissue of the host which still later assumed a structure peculiar for the fascia.

Subject Categories:

  • Medicine and Medical Research

Distribution Statement:

APPROVED FOR PUBLIC RELEASE