Accession Number:

AD0645452

Title:

ABERRANT CORNEAL EPITHELIAL CELLS PRODUCED BY RUBY LASER IRRADIATION,

Descriptive Note:

Corporate Author:

EDGEWOOD ARSENAL MD

Personal Author(s):

• Parr,W. H.
• Fisher,Robert S.

Report Date:

1966-10-31

Pagination or Media Count:

31.0

Abstract:

Rat corneas were exposed to either 4 joules per sq cm or 8 joules per sq cm and were harvested at varying times following laser exposure. Corneal whole mounts were evaluated for changes in either the differential mitotic cell count or the mitotic index. Ruby laser radiation 6,943 A produces aberrations in the corneal epithelium of the rat. At 8 joules per sq cm both interphase cells and cells in active mitosis were obviously altered. At 4 joules per sq cm aberrant corneal epithelial cells became apparent immediately after laser irradiation, and some were still present 30 days later. The mechanism by which laser radiation alters the cornea remains obscure. Author

Descriptors:

• *LASERS
• *CORNEA
• WOUNDS AND INJURIES
• PATHOLOGY
• CELL DIVISION
• MITOSIS
• THERMAL RADIATION
• HISTOLOGICAL TECHNIQUES
• SURGERY
• RATS
• EYE
• RADIATION HAZARDS

Subject Categories:

• Medicine and Medical Research
• Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE