Accession Number:

AD0644987

Title:

VIRUS GROWTH - GENE REPRESSION HYPOTHESIS OF RADIATION PROTECTION BY AUXIN ANALOGUES.

Descriptive Note:

Research communication no. 14,

Corporate Author:

DOUGLAS AIRCRAFT CO INC HUNTINGTON BEACH CALIF ADVANCED RESEARCH LAB

Personal Author(s):

Report Date:

1966-07-01

Pagination or Media Count:

23.0

Abstract:

A working hypothesis is developed which postulates 1 that death from radiation sickness in mammals is to an appreciable extent the result of the activation of initially latent but potentially cytopathic viruses, and 2 that a radiation-protective auxin analogue blocks such activation by allosterically stabilizing an active form of an auxin-sensitive repressor of a viral gene. The phenomena of lysogeny and virogeny are used as models to develop this hypothesis. Author

Subject Categories:

  • Biochemistry
  • Radiobiology
  • Microbiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE