Accession Number:
AD0644987
Title:
VIRUS GROWTH - GENE REPRESSION HYPOTHESIS OF RADIATION PROTECTION BY AUXIN ANALOGUES.
Descriptive Note:
Research communication no. 14,
Corporate Author:
DOUGLAS AIRCRAFT CO INC HUNTINGTON BEACH CALIF ADVANCED RESEARCH LAB
Personal Author(s):
Report Date:
1966-07-01
Pagination or Media Count:
23.0
Abstract:
A working hypothesis is developed which postulates 1 that death from radiation sickness in mammals is to an appreciable extent the result of the activation of initially latent but potentially cytopathic viruses, and 2 that a radiation-protective auxin analogue blocks such activation by allosterically stabilizing an active form of an auxin-sensitive repressor of a viral gene. The phenomena of lysogeny and virogeny are used as models to develop this hypothesis. Author
Descriptors:
Subject Categories:
- Biochemistry
- Radiobiology
- Microbiology
- Pharmacology