Accession Number:

AD0642077

Title:

DYNAMICS OF MULTIPLICATION OF THE VEE VIRUS IN TISSUE CULTURE CELLS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Report Date:

1965-09-01

Pagination or Media Count:

10.0

Abstract:

The virus of Venezuelan equine encephalomyelitis is capable of agglutinating goose erythrocytes at a pH of 5.8--6.0. The threshold of infectivity which is necessary for the exposure of VEE hemagglutinins comprises 4.6--5.7 lg TCD50 1,300,000--2,600,000 plaque forming units. The reaction of hemadsorption makes it possible to expose the multiplication of VEE in 6--9 hours following infection of a sensitive culture. The RGA and the reaction of hemadsorption may be used for determining the dynamics of multiplication of VEE and the early diagnosis of this virus. A prolonged liberation of virus particles into the surrounding medium is characteristic for VEE.

Subject Categories:

  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE