DYNAMICS OF MULTIPLICATION OF THE VEE VIRUS IN TISSUE CULTURE CELLS
ARMY BIOLOGICAL LABS FREDERICK MD
Pagination or Media Count:
The virus of Venezuelan equine encephalomyelitis is capable of agglutinating goose erythrocytes at a pH of 5.8--6.0. The threshold of infectivity which is necessary for the exposure of VEE hemagglutinins comprises 4.6--5.7 lg TCD50 1,300,000--2,600,000 plaque forming units. The reaction of hemadsorption makes it possible to expose the multiplication of VEE in 6--9 hours following infection of a sensitive culture. The RGA and the reaction of hemadsorption may be used for determining the dynamics of multiplication of VEE and the early diagnosis of this virus. A prolonged liberation of virus particles into the surrounding medium is characteristic for VEE.