Accession Number:

AD0641749

Title:

EFFECT OF SINGLE AND REPEATED TETRACYCLINE ADMINISTRATION ON THE PHAGOCYTIC FUNCTION OF RETICULENDOTHELIAL SYSTEMS

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

• Kalinina, N. A.
• Kivman, G. Ya.

Report Date:

1964-08-01

Pagination or Media Count:

6.0

Abstract:

It was previously established that single administration of chlortetracycline and oxytetracycline to white mice stimulates the absorptive function of the reticulo-endothelial system RES in several cases, depending on the dose of the preparation. Clinical use of tetracyclines is practically never restricted to single administration of the preparation therefore it is important to know whether their stimulating effects on the RES are retained upon repeated administration. The effect of single and repeated administration of chlortetracycline, tetracycline, and oxytetracycline on the absorptive function of mouse RES were studied.

Descriptors:

• *RETICULOENDOTHELIAL SYSTEM
• USSR
• STIMULATION(PHYSIOLOGY)
• DOSAGE
• TRANSLATIONS
• MICE
• STAPHYLOCOCCUS
• BIOLOGICAL ABSORPTION

Subject Categories:

• Microbiology
• Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE