THE CONTROL OF NUCLEIC ACID SYNTHESIS IN THE SALIVARY GLANDS OF RHYNCHOSCIARA ANGELAE.
Final rept. Aug 65-Jul 66,
SAO PAULO UNIV (BRAZIL) BIOCHEMISTRY LAB
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Methods were developed for extraction of RNA from salivary glands of Rhynchosciara, yielding high quality preparation as judged by hydrodinamic properties. By this method and pulse labeling the synthesis of RNA in the glands throughout larval development was studied. The principal class of RNA synthesized before the appearance of the large puffs is a 35S RNA. This RNA is subsequently transformed into ribosomal RNA. After appearance of the large puffs one observes almost complete inhibition of synthesis of ribosomal precursor. This correlation indicates the material produced in puffs is important in control of synthesis of RNA. Author
- Anatomy and Physiology