Accession Number:

AD0640614

Title:

EFFECTIVENESS OF SMALL EXTERNAL EPICONDYLAR LEAD CUFFS AGAINST LETHAL X-RADIATION IN DOGS,

Descriptive Note:

Corporate Author:

NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF

Report Date:

1966-10-19

Pagination or Media Count:

28.0

Abstract:

Dogs were exposed to 250 kvp X radiation while bearing a small external lead shield weighing about 600 grams around the limb epicondyle. Such shielding permitted survival after otherwise lethal doses up to 1000 R a dose approximately 3 times the LD50. The protection was characterized by a critical recovery in the peripheral leucocyte counts usually observable by 12 days postirradiation. A single lead cuff was also effective against a 600 R dose of 1 Mvp X rays but not after 800 R. However, protection against mortality was evident at this radiation dose when double or triple layers of lead shield were employed. Attenuation of the radiation dose under these conditions was measured by means of lithium fluoride dosimeters appropriately placed under the lead cuff and also on a dog phantom. The theoretical basis for the findings is discussed in terms of critical functional repopulation of peripheral hemopoietic and lymphoid tissue sites via cellular seeding from the shielded marrow. It is suggested that such shielding may be practically feasible under certain military and medical circumstances. Author

Subject Categories:

  • Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE