Accession Number:

AD0640048

Title:

BACTERIOLOGICAL DIAGNOSIS OF ANTHRAX (IN AN EXPERIMENT) IN THE FIRST DAYS FOLLOWING TREATMENT

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1965-06-01

Pagination or Media Count:

3.0

Abstract:

An experiment was performed to determine how rapidly under the influence of medical treatment the organism is free of the anthrax causative agent. Rabbits were infected subcutaneously with an 0.01 ml broth culture of B. anthracis, and after 24 and 48 hours a medicinal preparation was administered to them. Immune serum, streptomycin and penicillin in various proportions were administered for treatment. For the expanse of 12 hours following each administration of preparation after each 2 hours the animals were subjected to a bacteriological investigation. It was possible to detect the anthrax causative agents following the first seeding, and then positive results of seedings were noted in 46, 52, 66, 70 and 72 hours following the beginning of treatment. Consequently, treatment, including specific treatment, was not an obstacle for bacteriological diagnosis. The observation showed that the most expressed medicinal effect was conditioned by streptomycin. Penicillin only retarded the development of the infectious process, but did not dispose of it completely the death of rabbits treated with penicillin began 7--8 days later than the control.

Subject Categories:

  • Medicine and Medical Research
  • Microbiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE