Accession Number:
AD0639794
Title:
FORMATION OF METHYLENE BRIDGES IN THE REACTION OF RIBONUCLEIC ACID WITH FORMALDEHYDE
Descriptive Note:
Corporate Author:
ARMY BIOLOGICAL LABS FREDERICK MD
Personal Author(s):
Report Date:
1965-07-01
Pagination or Media Count:
11.0
Abstract:
From RNA, processed with formaldehyde, a product of the condensation of adenosine with formaldehyde was isolated. It was identified by chromatographic mobility and UV spectrum as methylene-bis-adenosine. In the alkaline hydrolyzate of RNA, treated with C14H2O, C14-methylene-bis-adenylic acid was detected chromatographically. Thus, experimental confirmation was obtained of the earlier expressed supposition concerning the formation of methylene bridges in the reaction of RNA with formaldehyde.
Descriptors:
Subject Categories:
- Biochemistry