Accession Number:

AD0639794

Title:

FORMATION OF METHYLENE BRIDGES IN THE REACTION OF RIBONUCLEIC ACID WITH FORMALDEHYDE

Descriptive Note:

Corporate Author:

ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s):

Report Date:

1965-07-01

Pagination or Media Count:

11.0

Abstract:

From RNA, processed with formaldehyde, a product of the condensation of adenosine with formaldehyde was isolated. It was identified by chromatographic mobility and UV spectrum as methylene-bis-adenosine. In the alkaline hydrolyzate of RNA, treated with C14H2O, C14-methylene-bis-adenylic acid was detected chromatographically. Thus, experimental confirmation was obtained of the earlier expressed supposition concerning the formation of methylene bridges in the reaction of RNA with formaldehyde.

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE