THE EFFECTIVENESS OF IMMUNIZATION THROUGH SCARIFIED SKIN WITH THE LIVE PLAGUE VACCINE
ARMY BIOLOGICAL LABS FREDERICK MD
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Conclusions A single inoculation with live plague vaccine through scarified skin imparted, to white mice and guinea pigs which were susceptible to plague, an immunity to the same degree as its inoculation under the skin, causing during this a clinically more expressed reaction than the subcutaneous vaccination. Of the live vaccines, prepared from the vaccine strain EV and strains no. 148, 149, and 150, the latter proved to be most effective. The live vaccine prepared from no. 150 caused a reaction analogous to the reaction to the administration of the EV strain.
- Medicine and Medical Research