THE EFFECT OF THE SYMPATHETIC VASCONSTRICTOR FIBRES ON THE DISTRIBUTION OF CAPILLARY BLOOD FLOW IN THE INTESTINE.
GOTEBORG UNIV (SWEDEN) DEPT OF PHYSIOLOGY
Pagination or Media Count:
Experiments are described which show that a marked and well sustained reduction in intestinal capillary filtration coefficient CFC is induced by vasoconstrictor fibre stimulation. This decrease in CFC is considered to reflect a widespread closure of precapillary sphincters with an obstruction of the corresponding capillaries. India ink injections indicate that this neurogenic obstruction of capillary flow particularly affects the intestinal mucosa. The fact that this marked neurogenic reduction of capillary blood supply to the mucosa takes place concomitantly with an only moderate increase of intestinal blood flow resistance suggests that a considerable redistribution of blood flow takes place within the intestine. The hemodynamic changes produced by the vasoconstrictor fibres in the intestine are compared with the drastically different situation in the skeletal muscles. Some functional implication of these findings are briefly discussed, as well as the possibility that intestinal blood flow is diverted to submucosal shunt vessels. Author
- Anatomy and Physiology