Accession Number:

AD0633742

Title:

PREPARATION OF POTENTIAL ANTIMALARIAL COMPOUNDS.

Descriptive Note:

Final rept. 1 Jul-15 Nov 65,

Corporate Author:

PENINSULAR CHEMRESEARCH INC GAINESVILLE FLA

Personal Author(s):

• Warner,Dale A.

Report Date:

1966-05-01

Pagination or Media Count:

21.0

Abstract:

Satisfactory procedures were developed and samples were prepared of the following compounds chloroacetone oxime, 1,4-bis2-oximinopropylpiperazine, 1,4-bis27-chloro-4-quinolyaminopropyl piperazine, 3,5-bis1-pyrrolidinomethyl-4-hydroxyacetanilide, and 3,5-bis1-pyrrolidinomethyl-4-hydroxyaniline hydrochloride. Work was stopped before the preparation of 2,6-bis1-pyrrolidinomethyl-4-7-chloro-4-quinolylaminophenol could be demonstrated. Author

Descriptors:

• (*ANTIMALARIALS
• SYNTHESIS(CHEMISTRY))
• (*ORGANIC NITROGEN COMPOUNDS
• ANTIMALARIALS)
• OXIMES
• CHLORINE COMPOUNDS
• ACETONES
• NITROGEN HETEROCYCLIC COMPOUNDS
• PYRROLES
• AMINES
• QUINOLINES
• PREPARATION

Subject Categories:

• Pharmacology
• Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE