Accession Number:

AD0633394

Title:

A STUDY OF RESEARCH METHODOLOGY FOR USE IN THE DEVELOPMENT OF ANTI-RADIATION AGENTS,

Descriptive Note:

Corporate Author:

FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY WASHINGTON D C LIFE SCIENCES RESEARCH OFFICE

Personal Author(s):

Report Date:

1966-01-15

Pagination or Media Count:

50.0

Abstract:

Contents Evaluation of research procedures employed in the screening and development of effective and safe anti-radiation agents Properties of an ideal anti-radiation agent Present status of research methodology employed in the search for and development of anti-radiation agents Nature and general manifestations of radiation damage and protection Methodology and significance of the mouse screening test and of other procedures employed in the search for anti-radiation agents and in the evaluation of radiation protection potency Survival of irradiated mice with and without a protective agent Determination of radiation protection by measurement of intracellular recovery and of the reparative proliferation of tissues Methods of assessment of radiation protection potency Chemical, pharmacologic, and toxicologic properties of anti-radiation agents.

Subject Categories:

  • Radiobiology
  • Pharmacology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE