CAPILLARY DEVELOPMENT DURING EXPOSURE TO CHRONIC HYPOXIA.
Rept. for 1 Jan-30 Jun 65,
FLORIDA UNIV GAINESVILLE COLL OF MEDICINE
Pagination or Media Count:
A group of 18 male rats weighing initially 110 to 131 gm. was exposed to a pressure altitude of 20,000 feet for 36 days in a decompression chamber. A similar group of 18 male rats was maintained at sea level for a like period. Hematocrits and organ-to-body-weight ratios were measured for heart, testes, adrenals, and kidneys in all animals at the end of the period. Capillary counts in heart, gracilis, and psoas muscles were made by utilizing a specific stain for endothelial cells. The hematocrit ratio and all measured organ-to-body-weight ratios increased significantly in the chronically hypoxic rats. A significant increase in capillary counts was also found in these animals. On the basis of these preliminary studies, it would appear that in chronic hypoxia, there is an increase in vascularity due to an increase in capillary number rather than an increased patency of existing vessels. Author
- Anatomy and Physiology
- Medicine and Medical Research