Accession Number:

AD0632954

Title:

SODIUM FLUX AND WATER TRANSPORT IN THE EVERTED RABBIT INTESTINAL SAC,

Descriptive Note:

Corporate Author:

NAVAL MEDICAL RESEARCH UNIT NO 2 TAIPEI (TAIWAN)

Report Date:

1966-05-02

Pagination or Media Count:

18.0

Abstract:

The everted intestinal sac prepared from adult rabbit ileum has unidirectional fluxes of sodium that can be measured with Na22 and Na24. The rates are linear for one hour. The net flux is from mucosa to serosa and the net values are about 10 of unidirectional fluxes net, approximately 1 micro Eqcm sqhr at 37C, pH 8.0, in Ringer phosphate-bicarbonate. In the same experiments, there is also net transport of water from mucosa to serosa. The sacs consume glucose, but glucose does not stimulate sodium or water transport. Raising the initial potassium concentration of 5 mEqL to 20 mEqL increases glucose consumption but does not alter sodium and water transport. The net transport of sodium is inhibited by KCN and HgCl2 and the unidirectional fluxes are decreased but not abolished. Author

Subject Categories:

  • Anatomy and Physiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE