FLUID AND SOLUTE SHIFTS ACROSS THE PERITONEAL MEMBRANE.
AEROMEDICAL RESEARCH LAB (6571ST) HOLLOMAN AFB N MEX
Pagination or Media Count:
Isosmotic solutions of mannitol were injected into the peritoneal cavities of 15 dogs. The volume of remaining fluid was measured at timed intervals after injection. The concentration of electrolytes quickly approached plasma levels, principal fluxes occurring during the first 2 hours. Changes in concentration reflected movement of water from the plasma into the intraperitoneal fluid which increased terminally to an average of 26.8 percent of injected volume. The osmolality of the peritoneal fluid terminally was higher than that of the plasma in all but three of the dogs. A computer method is presented for calculating the rate constants for fluxes of solutes in and out of the peritoneal cavity. Author
- Anatomy and Physiology