Accession Number:

AD0632593

Title:

NUCLEOPHILIC DISPLACEMENTS ON PHOSPHONIC ACID ESTERS.

Descriptive Note:

Quarterly rept. no. 5, 1 Sep 65-30 Apr 66,

Corporate Author:

BROWN UNIV PROVIDENCE R I

Report Date:

1966-04-30

Pagination or Media Count:

13.0

Abstract:

Data on the reaction of p-nitrophenyl methylphosphonate with a variety of hydroxamic acids is reported and discussed. Various experimental difficulties served to limit the number of successful trials. An attempt to obtain Bronsted plot for the observed data showed a small dependence upon the basicity of the hydroxamic acid. Consideration is also given to the reaction of p-nitrophenyl methylphosphonate with a series of tertiary amines. A Bronsted plot of amine pKa vs. log K2 second order rate constant has a slope of 0.31. It was also observed that only freshly distilled amines gave consistent rate data. A small rate enhancement was noted with an increase in ionic strength. Author

Subject Categories:

  • Organic Chemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE