Accession Number:

AD0632261

Title:

ANTICHOLINESTERASE PROPERTIES OF SOME O-ETHYL S-ALKYL METHYLTHIOPHOSPHONATES. 2. KINETICS OF INHIBITION OF CHOLINESTERASE AND ACETYLCHOLINESTERASE BY O-ETHYL S-N -ALKYL METHYLTHIOPHOSPHONATES,

Descriptive Note:

Corporate Author:

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Report Date:

1966-04-29

Pagination or Media Count:

14.0

Abstract:

The kinetics of the interaction of O-ethyl S-n-alkyl methylthiophosphonates with horse serum cholinesterase and bovine erythrocyte acetylcholinesterase was investigated. The water-alkyl hydrolysis constants of the studied compounds were determined. The anticholinesterase activity of the O-ethyl S-n-alkyl methylthiophosphonates strongly depends upon the length of the alkyl radical. Author

Subject Categories:

  • Biochemistry

Distribution Statement:

APPROVED FOR PUBLIC RELEASE