A STUDY OF FLUORESCENT PRODUCTS IN THE URINE OF RATS EXPOSED TO IONIZING RADIATION.
Progress rept. Nov 64-Oct 65,
NORTHROP SPACE LABS HAWTHORNE CALIF
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The excretion of fluorescent products in the urines of nonirradiated rats and rats exposed to a lethal dose of ionizing radiation was investigated. Fractionation of the urine extracts by gel filtration chromatography yielded eleven fluorescent fractions. Several fractions in the urines of the irradiated animals showed marked decreases in total fluorescence. A new fluorescent fraction was found exclusively in the post-irradiation urines. In addition, other differences between the irradiated and nonirradiated animals were found by means of thin-layer chromatography. Author