MECHANISM OF RODENTICIDAL ACTIVITY OF GLIRICIDIA SEPIUM.
Final technical rept., Jul 63-Dec 65,
NAVAL CIVIL ENGINEERING LAB PORT HUENEME CALIF
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A study was made of the mechanism by which Gliricidia sepium Yaite exerts its rodenticidal properties. Extraction of the leaves of this plant, followed by physical and chemical fractionation, revealed the presence of coumarin as a constituent of the phenolic fraction. Consideration of the conditions under which these leaves are used as rodenticides, the known bacterial conversion of coumarin into the hemorrhagic agent dicoumerol, and pathological evidence in rats fed on incubated leaves point to coumarin as the basis for the rodenticidal properties of this plant. Author