Accession Number:

AD0626682

Title:

BONE MARROW AS THE MAJOR SOURCE OF POTENTIAL IMMUNOLOGICALLY COMPETENT CELLS IN THE ADULT MOUSE,

Descriptive Note:

Corporate Author:

NAVAL RADIOLOGICAL DEFENSE LAB SAN FRANCISCO CALIF

Personal Author(s):

• Tyan,Marvin L.
• Cole,Leonard J.

Report Date:

1965-12-08

Pagination or Media Count:

12.0

Abstract:

Groups of F1 hybrid mice A x B were sublethally irradiated and injected with cells from various lymphoid tissues of adult parental strain A mice. Spleen and lymph node cells and cells from the thymus of the survivors were then injected into an F1 hybrid of another type A x C. A significant number of deaths occurred among the secondary hosts only when they had received spleen cells from mice which had been injected with adult bone-marrow cells. Author

Descriptors:

• *IMMUNOLOGY
• *BONES
• *RADIATION EFFECTS
• BONE MARROW
• RADIATION
• IMMUNITY
• SUBLETHAL DOSAGE
• SPLEEN
• CELLS(BIOLOGY)
• THYMUS
• HEMATOPOIETIC SYSTEM
• MICE

Subject Categories:

• Medicine and Medical Research
• Radiobiology

Distribution Statement:

APPROVED FOR PUBLIC RELEASE